Ames 24-Well Agar Test for Accurate Mutagenicity Testing
What is the Ames 24-Well Agar Test?
Using a microwell format, the GLP Ames test, specifically the Ames 24-well Agar test, provides predictivity of the OECD 471 Ames study in comparable conditions, using just 5% of the test item. It is also conducted in solid agar. This makes the 24-well version of the Ames test highly amenable to screening, with TA98 & TA100 providing coverage for most known mutagenic substances.
If you would like more details on how Gentronix can support your project by conducting the Ames 24-Well Agar Test, please contact a team member or submit an enquiry at enquiries@gentronix.co.uk.

Advantages of using the 24-Well Agar Method
– Agar based, TA98 & TA100 ± S9
– Results comparable to full plate format
– Requires 20 mg compound
– Quick, cost-effective, high-quality results
Key Specifications of the Ames 24-Well Agar Test
24-well Test strains | TA98, TA100 |
Metabolic activation | Typically, induced rat liver S9, other sources available |
Replicates | 3 Wells per test concentration |
Typical test item requirements | 20mg |
Study Duration | < 3 Weeks |
Endpoint | Mutagenicity |