Ames 24-well Agar Test


Using a microwell format, the Ames 24-well Agar test provides predictivity of the OECD 471 Ames study in comparable conditions but using just 5% of the test item and is also conducted in solid agar. This makes the 24-well version of the Ames test highly amenable to screening, with TA98 & TA100 providing coverage for the vast majority of all known mutagenic substances.

corning 6.5mm Transwell with 3.0 um Pore Polycarbonate Membrane Insert, Sterile for 24-well Mini Ames

Advantages for Screening

– Agar based, TA98 & TA100 ± S9
– Results comparable to full plate format
– Requires 20 mg compound
– Quick, cost effective, high quality results

24-well Test strainsTA98, TA100
Metabolic activationTypically, induced rat liver S9, other sources
Replicates3 Wells per test concentration
Typical test item requirements20mg
Study Duration< 3 Weeks

Predictive Toxicology, Expertly Delivered